Noma is an opportunistic infection promoted by extreme poverty. It evolves rapidly from a gingival inflammation to grotesque orofacial gangrene. Cancrum oris. Prevalence: Unknown; Inheritance: ; Age of onset: Childhood; ICD A; OMIM: ; UMLS: C; MeSH: D; GARD: Cancrum oris or noma (from the Greek nomein, “to devour”)1 is a “gangrenous affection of the mouth, especially attacking children in whom the constitution is.

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Most children who get the disease are between the ages of two and six years old.

Confounding interactions of malnutrition cancruj infection. Aesthetic restoration of facial defect caused by cancrum oris: A devastating orofacial gangrene. Indian J Plast Surg ; If the lesion is still intrabuccal and limited, antibiotics may also prevent progression of the disease in some cases. Delayed treatment will not allow a return to status quo ante.

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.

Once the cicatrisation stage is complete, stepwise reconstructive surgery aimed at relieving the stricture of the mouth and then reconstruction of the mandible and maxilla, cheek, lips and nose can be considered.

It occurs in malnourished children in areas where sanitation and cleanliness are lacking. Isolation of Fusobacterium necrophorum from cancrum oris noma O. In some cases, this condition can be deadly if it is not treated. In other projects Wikimedia Commons. They may also have a weakened immune system.


Bacteroides fragilis Cncrum forsythia Capnocytophaga canimorsus Porphyromonas gingivalis Prevotella intermedia. Spontaneous resolution of the disease is associated with the formation of extremely dense and fibrous scars that may lead to osseous ankylosis between the mandible and maxilla or the mandible and the malar bone. From Wikipedia, the free encyclopedia.

Oral mucosa — Lining of mouth. Cancrum oris or noma is a rapidly spreading gangrenous stomatitis which occurs chiefly in debilitated or malnourished children, destroying the soft and hard tissue structures.

Noma (disease)

Bacterial Infections Read more. Am J Trop Med Hyg ; Survivors suffer the two-fold afflictions of oro-facial mutilation and functional impairment, which require a canvrum, financially prohibitive surgical reconstruction.

Summary and related texts. Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: J Can Dent Assoc ; The mucous membranes of the mouth develop ulcersand rapid, painless tissue degeneration ensues, which can degrade tissues of the bones in the face. Saunders Book Company, Orofacial soft tissues — Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig’s angina Macrostomia Melkersson—Rosenthal syndrome Microstomia Noma Oral Crohn’s disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans.


The dehumanizing oro-facial gangrenous lesion affects predominantly children ages 2 to 16 years, particularly in sub-Saharan Africa, where the estimated frequency in some communities varies from 1 to 7 cases per population.

The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. Dent Clin North Am ; Temporomandibular jointsmuscles of mastication and malocclusions — Jaw joints, chewing muscles and bite abnormalities Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overeruption Overjet Prognathia Retrognathia Scissor bite Maxillary hypoplasia Temporomandibular joint dysfunction.

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.

Children and other noma survivors in Africa are helped by a few international charitable organizationssuch as Facing Africaa UK registered charity that helps affected Ethiopian, and Swiss charity Winds of Hope. Infections and malnutrition impair the immune system, and this is the common denominator for the occurrence of noma.

Infobox medical condition new. Photograph of the patient with the nasogastric tube Click here to view.